Background: Chronic graft versus host disease (ch.GVHD) is the most frequent late complication after allogenic stem-cell transplantation. Systemic immunosuppressive agents are usually required to control the disease. Psoralen plus UVA (PUVA) has been used for the treatment of ch.GVHD with variable beneficial effects. The objective of this study was to assess the efficacy and safety of a r...

A reliable, simple and sensitive reversed-phase high-performance liquid chromatographic method was developed for determination of losartan in plasma .Separation is achieved by HPLC after direct injection on a CN (250*4.6 mm) analytical column with a mobile phase composed of sodium hydrogen phosphate buffer acetonitrile tetrahydrofurane methanol and phosphoric acid (0.1:5 :4 :21 :69.9 ) V/V% adj...

Receptor-mediated signal transduction modulates complex cellular behaviours such as cell growth, migration and differentiation. Although photoactivatable proteins have emerged as a powerful tool for controlling molecular interactions and signalling cascades at precise times and spaces using light, many of these light-sensitive proteins are activated by ultraviolent or visible light, which has l...

BACKGROUND Different investigation showed that 5-methoxypsoralen and 8- methoxypsoralen reduce birth rates in the rats. OBJECTIVE In this study we worked out the effect of methoxsalen together with ultraviolent A (UVA) radiation on mature Balb/C mice spermatogenesis. MATERIALS AND METHODS The LD50 standard was determined 160 mg/kg and the UVA dose which causes erythema was calculated 0.046 ...

In this study, it was aimed to optimize the biosynthesis of silver nanoparticles with a Box-Behnken design. The white propolis extract utilized as reduction and stabilizing agent. synthesized using solution were optimized by design considering effect certain independent variables such microwave power, time, concentration AgNO3 (silver nitrate). A quadratic polynomial model used in mathematical ...

background: different investigation showed that 5-methoxypsoralen and 8- methoxypsoralen reduce birth rates in the rats. objective: in this study we worked out the effect of methoxsalen together with ultraviolent a (uva) radiation on mature balb/c mice spermatogenesis. materials and methods: the ld50 standard was determined 160 mg/kg and the uva dose which causes erythema was calculated 0.046 j...

This study evaluated the electrocardiograph effects of Abelmoschus esculentus and its isolated compounds on Rana temporaria (frog) heart. Cardiovascular disease is one major causes mortality which contribute to about 57 million deaths as disclosed by WHO in 2002. There have been many therapeutic approaches reduce death rate from cardiovascular include use herbal drugs plants. The whole fruit (O...